Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Jan 2013
Multicenter StudyHypersensitivity reactions to Patent Blue V in breast cancer surgery: a prospective multicentre study.
An increasing number of immediate hypersensitivity reactions (HSR) have been reported after the use of Patent Blue V (PBV) for breast cancer surgery. This is the first study to publish prospective data with systematic allergological assessment. ⋯ An incidence rate of one in 300 HSR to PBV was observed for patients exposed to PBV during sentinel lymph node detection. This rate is higher than rates reported after the use of neuromuscular blocking agents, latex or antibiotics.