Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Apr 2013
Metabolic effects of three different inotropic strategies in the newborn piglet myocardium.
Neonates undergoing congenital heart surgery frequently need post-operative inotropic support. Knowledge about the effect of inotropes on myocardial metabolism in the newborn heart is limited, and the choice of inotropic therapy is based mainly on evidence from studies in adults. The aim of this study was to compare the effect of three inotropic strategies on the myocardial metabolism in a neonatal pig model. ⋯ Milrinone and adrenaline induced significantly higher lactate levels in neonatal piglets. The increase was not caused by myocardial ischaemia, but rather due to a beta-stimulation-induced glycolysis.
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Acta Anaesthesiol Scand · Apr 2013
Retraction Of PublicationRetraction. Granisetron reduces incidence of nausea and vomiting after breast surgery.
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Acta Anaesthesiol Scand · Apr 2013
Retraction Of PublicationRetraction. Preoperative oral granisetron prevents postoperative nausea and vomiting.
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Acta Anaesthesiol Scand · Apr 2013
Minimal alveolar concentration of sevoflurane for maintaining bispectral index below 50 in morbidly obese patients.
Morbid obesity is associated with important differences in pharmacokinetics and pharmacodynamics. The aim of this study was to determine minimum alveolar concentration of sevoflurane for maintaining bispectral index (BIS) below 50 (MACBIS50 ) in morbidly obese patients undergoing bariatric surgery using the Continual Reassessment Method (CRM) method. ⋯ The calculated values (1.8% and 1.6%) were higher than that previously reported in normal adult patients (0.97%; 95% CI 0.89-1.1%) and less than that reported in children (2.8%; 95% CI 2.7-3.1%).