Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Apr 2015
Review Meta AnalysisIntravenous ketamine during spinal and general anaesthesia for caesarean section: systematic review and meta-analysis.
Intravenous ketamine has been used during general and regional anaesthesia for caesarean section. No systematic review and meta-analysis on the desired effects and adverse effects of ketamine administration during caesarean section have yet been performed. ⋯ We conclude that ketamine enhances post-operative analgesia after caesarean section under spinal anaesthesia. There is a paucity of data for several maternal adverse effects as well as for neonatal well-being. Further studies are needed for general anaesthesia.
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Acta Anaesthesiol Scand · Apr 2015
Review Meta AnalysisPre-operative fibrinogen supplementation in cardiac surgery patients: an evaluation of different trigger values.
Pre-operative fibrinogen levels are negatively associated with postoperative bleeding in cardiac surgery patients. The guidelines of the European Society of Anaesthesiology consider the possibility of a prophylactic pre-operative supplementation in patients with fibrinogen levels<`3.8 g/l. The present study is a reanalysis of published data aimed to define the diagnostic accuracy of different values of pre-operative fibrinogen levels in predicting severe post-operative bleeding. ⋯ Correction of pre-operative fibrinogen levels below 3.8 g/l would lead to an excessive rate of inappropriate interventions. Values below 2.5 g/l could be considered.