Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Feb 2017
ReviewInterventions to reduce cognitive impairments following critical illness: a topical systematic review.
Critical illness is associated with cognitive impairments. Effective treatment or prevention has not been established. The aim of this review was to create a systematic summary of the current evidence concerning clinical interventions during intensive care admission to reduce cognitive impairments after discharge. ⋯ None of the interventions had significant positive effects on cognitive impairments following critical illness. Quality was negatively affected by study limitations, imprecision and indirectness in evidence. Clinical research on cognition is feasible, but large, well designed trials with a specific aim at reducing cognitive impairments are needed.