Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · May 2017
Randomized Controlled TrialPost-operative pain relief using local infiltration analgesia during open abdominal hysterectomy: a randomized, double-blind study.
Post-operative pain is common and often severe after open abdominal hysterectomy, and analgesic consumption high. This study assessed the efficacy of local infiltration analgesia (LIA) injected systematically into different tissues during surgery compared with saline on post-operative pain and analgesia. ⋯ Systematically injected local infiltration analgesia for pain management was superior to saline in the primary endpoint, resulting in significantly lower rescue morphine requirements during 0-24 h, longer time to first analgesic request and lower early post-operative pain intensity.