Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Nov 2018
Randomized Controlled TrialLactate, lactate clearance and outcome after cardiac arrest: A post-hoc analysis of the TTM-Trial.
Admission lactate and lactate clearance are implemented for risk stratification in sepsis and trauma. In out-of-hospital cardiac arrest, results regarding outcome and lactate are conflicting. ⋯ Admission lactate and 12-hour lactate values were independently associated with 30-day mortality after out-of-hospital cardiac arrest while 12-hour lactate clearance was not. The clinical value of lactate as the sole predictor of outcome after out-of-hospital cardiac arrest is, however, limited.
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Acta Anaesthesiol Scand · Nov 2018
Randomized Controlled TrialPressure measurement in the upper esophagus during cricoid pressure: A high-resolution solid-state manometry study.
The use of cricoid pressure is controversial, and its ability to occlude the esophagus has been questioned. In this study, high-resolution solid-state manometry was used to analyze pressure changes in the upper esophagus from cricoid pressure during modified rapid sequence induction. This is a secondary analysis of data from a previous study. ⋯ This study using high-resolution solid-state manometry under clinically relevant conditions shows that 30 N cricoid pressure generates high pressure in the area of the UES, far exceeding the levels previously considered necessary to prevent regurgitation. Additional studies are needed to clarify the effectiveness of cricoid pressure in preventing passive regurgitation before it is rejected as a part of rapid sequence induction.