Acta anaesthesiologica Scandinavica
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Acta Anaesthesiol Scand · Jul 2018
Randomized Controlled TrialSensory distribution of the lateral femoral cutaneous nerve block - a randomised, blinded trial.
The lateral femoral cutaneous nerve (LFCN) block may be used for post-operative pain management in patients undergoing total hip arthroplasty. The aim of this trial was to investigate the sensory coverage of the posterior and the lateral incision lines and the involvement of the femoral nerve after an LFCN block. ⋯ An LFCN block consisting of 8 ml 0.75% ropivacaine had limited coverage of the posterior and lateral incision lines.
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Acta Anaesthesiol Scand · Jul 2018
Randomized Controlled TrialRandomized controlled trial of intra-articular ketorolac on pain and inflammation after minor arthroscopic knee surgery.
Ketorolac is an effective non-steroidal anti-inflammatory drug, commonly used with local anaesthetics as part of local infiltration analgesia protocols following orthopaedic surgery. However, systemic uptake and drug action may be the major mechanism after local infiltration. The aims of this project were to study the effects of a small, systemically ineffective dose of ketorolac given intra-articularly for post-operative pain and also to study synovial inflammatory biomarkers. We investigated whether ketorolac affects pro-inflammatory biomarkers in an in vitro model, as well. ⋯ Ketorolac prescribed at a low dose intra-articularly does not produce any detectable analgesic effect after minor knee surgery.
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Acta Anaesthesiol Scand · Jul 2018
Randomized Controlled TrialA pilot study of hyperoxemia on neurological injury, inflammation and oxidative stress.
Normobaric hyperoxia is used to alleviate secondary brain ischaemia in patients with traumatic brain injury (TBI), but clinical evidence is limited and hyperoxia may cause adverse events. ⋯ Higher fraction of inspired oxygen did not increase blood concentrations of markers of oxidative stress, inflammation or neurological injury or the incidence of pulmonary complications in severe TBI patients on mechanical ventilation.
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Acta Anaesthesiol Scand · Jul 2018
Randomized Controlled TrialEffect of adding midazolam to bupivacaine during rectus sheath block: a randomised controlled trial.
Various adjuvants have been tried to improve quality and increase duration of local anaesthetics during various nerve blocks. We aimed to evaluate the effect of adding midazolam to bupivacaine on rectus sheath (RS) block in patients undergoing umbilical or epigastric hernia repair. ⋯ Midazolam addition to bupivacaine for RS blockade provided adjuvant analgesia as supported by less morphine consumption, longer duration of analgesia, and lower VAS score.