Archives of orthopaedic and trauma surgery
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Arch Orthop Trauma Surg · Oct 2019
Review Meta AnalysisBetter outcomes with patellar resurfacing during primary total knee arthroplasty: a meta-analysis study.
Total knee arthroplasty (TKA) is a feasible and cost-effective procedure. However, resurfacing of the patella sparks a heated debate. Anterior knee pain after TKA was supposed to be correlated to the patellofemoral joint, and the resurface of the patella was believed to be effective to avoid this complication. ⋯ Level II, meta-analysis of prospective clinical trials.
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Arch Orthop Trauma Surg · Oct 2019
Review Meta AnalysisFusion rates for odontoid fractures after treatment by anterior odontoid screw versus posterior C1-C2 arthrodesis: a meta-analysis.
For odontoid fractures, surgical treatment approaches including anterior odontoid screw fixation approach and the posterior C1-C2 arthrodesis approach are generally adopted in practice. However, the choice of different surgical procedures remains controversial. In addition to surgical technique, the fusion rate is an important factor contributing to the clinical efficacy. Therefore, this study was aimed to investigate the discrepancy in fusion rate between these two surgical approaches through synthesizing the currently available evidence on the topic. ⋯ Elderly patients (≥ 60 years) underwent posterior C1-2 arthrodesis fixation shows higher fusion rates in developed countries comparing with patients who underwent anterior odontoid screw fixation. Overall, there is no significant discrepancy between these two surgical approaches. However, the conclusion should be verified by further study enrolling larger sample size.
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Arch Orthop Trauma Surg · Oct 2019
Denosumab treatment for giant-cell tumor of bone: a systematic review of the literature.
Denosumab is a human monoclonal antibody (mAb) that specifically inhibits tumor-associated bone lysis through the RANKL pathway and has been used as neoadjuvant therapy for giant-cell tumor of bone (GCTB) in surgical as well as non-surgical cases. The purpose of this systematic review of the literature, therefore, is to investigate: (1) demographic characteristics of patients affected by GCTBs treated with denosumab and the clinical impact, as well as, possible complications associated with its use (2) oncological outcomes in terms of local recurrence rate (LRR) and development of lung metastasis, and (3) characteristics of its treatment effect in terms of clinical, radiological, and histological response. ⋯ IV.