International journal of obstetric anesthesia
-
Int J Obstet Anesth · Jan 2001
Randomized Controlled Trial Clinical TrialA comparison of bupivacaine-fentanyl-morphine with bupivacaine-fentanyl-diamorphine for caesarean section under spinal anaesthesia.
In a randomised double-blind trial, postoperative analgesia and side effects of intrathecal morphine 0.1 mg and intrathecal diamorphine 0.25 mg were compared. Sixty women were randomised to receive intrathecal injection of 12.5 mg hyperbaric bupivacaine and 12.5 microg fentanyl with either morphine 0.1 mg (group M), or diamorphine 0.25 mg (group D). All women received 100 mg diclofenac rectally at the end of surgery and were given intravenous morphine via a patient controlled analgesia (PCA) system. ⋯ There was no significant difference between the groups in the number of women vomiting in the 24-h period. The two groups were comparable for pruritus and drowsiness. We conclude that 0.25 mg subarachnoid diamorphine is a suitable alternative to 0.1 mg morphine for post caesarean section analgesia.
-
Int J Obstet Anesth · Jan 2001
Long-term morbidity following dural puncture in an obstetric population.
Immediate and long-term symptoms, particularly headache, are recognised complications of dural puncture. To investigate long-term symptoms, a case-controlled retrospective questionnaire study was performed. The questionnaire was sent to 194 mothers who had suffered either accidental dural puncture during the placement of an epidural catheter or had developed a significant headache following spinal anaesthesia. ⋯ There was increased reporting of new long-term headache and neckache in the spinal study group and an increased reporting of new long-term backache in the accidental dural puncture group compared to the epidural controls. These symptoms had a significant impact upon the mother's daily life and in some instances lasted for years. Disappointingly, although epidural blood patching was beneficial in the short term, it failed to produce any reduction in the incidence of long-term symptoms.
-
Int J Obstet Anesth · Oct 2000
Randomized Controlled Trial Clinical TrialPostoperative intraspinal opioid analgesia after caesarean section; a randomised comparison of subarachnoid morphine and epidural pethidine.
A randomised, blinded clinical trial was performed to evaluate intraspinal opioid analgesic techniques after caesarean section. Healthy term parturients having elective caesarean section under combined spinal-epidural anaesthesia were allocated to one of three groups. Postoperative analgesia, including non-steroidal anti-inflammatory drugs, was provided using either pethidine patient-controlled epidural analgesia (group PCEA) or subarachnoid morphine 200 microg, the latter supplemented as required with patient-controlled intravenous pethidine (group SMPCIA) or oral paracetamol and codeine (group SMO). ⋯ Patient satisfaction was similar, although women in group SMO were least likely to choose this approach again (P<0.05). We concluded that all three techniques provided effective analgesia for a prolonged period postoperatively. Better pain relief, but more opioid-related side effects, resulted from subarachnoid morphine 200 microg, and re-evaluation of reduced doses of subarachnoid morphine may be warranted.
-
Int J Obstet Anesth · Oct 2000
Anaesthesia for emergency caesarean section in a parturient with bleeding placenta praevia and a potentially malignant hyperthermia-susceptible fetus.
A parturient who was 35 weeks' pregnant by her husband who was known to be susceptible to malignant hyperthermia, required anaesthesia for caesarean section for bleeding placenta praevia. The patient was considered to be haemodynamically stable and the procedure was carried out uneventfully under subarachnoid block. Anaesthesia was conducted as for an individual who is susceptible to malignant hyperthermia. The combination of the potential susceptibility to malignant hyperthermia of the fetus, and the problems of bleeding placenta praevia, produced an unusual clinical situation with potential conflict of interests when choosing the anaesthetic technique.
-
Int J Obstet Anesth · Oct 2000
Randomized Controlled Trial Clinical TrialA randomised, double-blind comparison of subarachnoid and epidural diamorphine for elective caesarean section using a combined spinal-epidural technique.
We have compared the quality of analgesia and incidence of side-effects from subarachnoid and epidural diamorphine for caesarean section, as part of a combined spinal-epidural technique. Sixty patients were studied in a randomised, double-blind, double-dummy assessment. The doses of diamorphine reflect current practice in our hospital and are close to optimal. ⋯ Postoperative nausea and vomiting were uncommon; 83% of patients in group 1 and 77% in group 2 had none. Subarachnoid and epidural diamorphine provided similar quality analgesia with a low incidence of emetic symptoms. However, pruritus was more common and more severe after subarachnoid diamorphine.