American journal of obstetrics and gynecology
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Am. J. Obstet. Gynecol. · Oct 1999
Rate of uterine rupture during a trial of labor in women with one or two prior cesarean deliveries.
We sought to determine whether there is a difference in the rate of symptomatic uterine rupture after a trial of labor in women who have had 1 versus 2 prior cesarean deliveries. ⋯ Women with a history of 2 prior cesarean deliveries have an almost 5-fold greater risk of uterine rupture than those with only 1 prior cesarean delivery.
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Am. J. Obstet. Gynecol. · Oct 1999
Randomized Controlled Trial Clinical TrialA randomized, double-blind trial of oral nifedipine and intravenous labetalol in hypertensive emergencies of pregnancy.
We sought to compare the efficacies of oral nifedipine and intravenous labetalol in the acute management of hypertensive emergencies of pregnancy. ⋯ Both oral nifedipine and intravenous labetalol are effective in the management of acute hypertensive emergencies of pregnancy; however, nifedipine controls hypertension more rapidly and is associated with a significant increase in urinary output.
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Am. J. Obstet. Gynecol. · Oct 1999
The relationship between placental histology and cervical ultrasonography in women at risk for pregnancy loss and spontaneous preterm birth.
Our objective was to determine whether there were any differences in the placental lesions of high-risk patients with versus without ultrasonographic evidence of cervical shortening between 15 and 24 weeks' gestation. ⋯ Acute inflammatory lesions of the placenta were more frequent in patients with second-trimester cervical shortening. These findings support that patients with cervical shortening in the second trimester are prone to acute placental inflammation.
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Am. J. Obstet. Gynecol. · Oct 1999
A systemic fetal inflammatory response and the development of bronchopulmonary dysplasia.
The purpose of this study was to test the hypothesis that a systemic fetal inflammatory response is a risk factor for the subsequent development of bronchopulmonary dysplasia in preterm neonates. ⋯ An elevated interleukin 6 concentration in umbilical cord plasma at birth is an independent risk factor for the development of bronchopulmonary dysplasia. These data support the concept that the injury responsible for bronchopulmonary dysplasia in a subset of neonates may begin before birth and is associated with the development of a fetal systemic inflammatory response, as determined by plasma concentrations of interleukin 6.
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Am. J. Obstet. Gynecol. · Oct 1999
Randomized Controlled Trial Clinical TrialA randomized, double-blind, hemodynamic evaluation of nifedipine and labetalol in preeclamptic hypertensive emergencies.
Our purpose was to compare the hemodynamic effects of orally administered nifedipine and intravenously administered labetalol in preeclamptic hypertensive emergencies. ⋯ Nifedipine increases cardiac index, whereas labetalol may not do so.