American journal of obstetrics and gynecology
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Am. J. Obstet. Gynecol. · Oct 1999
Randomized Controlled Trial Clinical TrialA randomized, double-blind trial of oral nifedipine and intravenous labetalol in hypertensive emergencies of pregnancy.
We sought to compare the efficacies of oral nifedipine and intravenous labetalol in the acute management of hypertensive emergencies of pregnancy. ⋯ Both oral nifedipine and intravenous labetalol are effective in the management of acute hypertensive emergencies of pregnancy; however, nifedipine controls hypertension more rapidly and is associated with a significant increase in urinary output.
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Am. J. Obstet. Gynecol. · Oct 1999
Randomized Controlled Trial Clinical TrialA randomized, double-blind, hemodynamic evaluation of nifedipine and labetalol in preeclamptic hypertensive emergencies.
Our purpose was to compare the hemodynamic effects of orally administered nifedipine and intravenously administered labetalol in preeclamptic hypertensive emergencies. ⋯ Nifedipine increases cardiac index, whereas labetalol may not do so.