Anaesthesia
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Randomized Controlled Trial Clinical Trial
The prevention of pain on injection. A study of the effect of intravenous lignocaine before methohexitone.
The effect of pre-injection of lignocaine 10 mg or physiological saline was assessed in a double blind trial on 100 unpremedicated day cases having a methohexitone induction. The incidence of pain was reduced from 64% to 22% using lignocaine.
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Randomized Controlled Trial Comparative Study Clinical Trial
Intubating conditions with ORG NC45. A preliminary study.
The case of tracheal intubation using two doses of the new steroid neuromuscular blocking compound ORG NC45 (Norcuron) 0.1 and 0.15 mg/kg was compared with a standard dose of pancuronium 0.1 mg/kg at 60, 90 and 120 seconds. The results did not reveal any statistically significant benefit of the new drug within 2 minutes of administration over the control.