Anaesthesia
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Controlled Clinical Trial
The effects of brief sevoflurane-nitrous oxide anaesthesia upon children's postoperative cognition and behaviour.
This study assessed the effects of brief sevoflurane-nitrous oxide anaesthesia on children's postoperative cognition, behaviour and physical morbidity. Forty-eight children aged 5-10 years undergoing anaesthesia without premedication for multiple dental extractions, and 48 control children, performed tests of choice reaction time, attention, psychomotor co-ordination and memory pre-operatively (baseline), prior to discharge and at 48 h (anaesthesia group only). Physical and psychological morbidity were recorded at 1 week. ⋯ However, measures of performance variability suggested the presence of residual impairment. Profound retrograde amnesia affected postoperative and 48-h recall of pictorial stimuli presented prior to anaesthesia, but recognition memory was unimpaired. Attention-seeking, tantrums, crying and nightmares were occurring more frequently in some 8-20% of children 1 week after the procedure.
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Randomized Controlled Trial Comparative Study
Inhalation induction using sevoflurane in children: the single-breath vital capacity technique compared to the tidal volume technique*.
The single-breath vital capacity technique is suitable for inhalation induction of anaesthesia, using sevoflurane in children aged > 5 years. The purpose of this randomised trial was to compare the single breath vital capacity technique with the conventional tidal volume technique. Seventy- three ASA 1 or 2 children were instructed during the pre-operative visit in the vital capacity technique. ⋯ The time to loss of the eyelash reflex was found to be reduced in the vital capacity group compared to the tidal volume group. The time to central myosis, to achieve bispectral index values 60 and 40, haemodynamic changes, respiratory events and side-effect incidences were similar in both groups. However, we found that the vital capacity technique was preferred by the children to the tidal volume technique.
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Comparative Study
Simulated clinical evaluation of four fluid warming devices*.
The fluid warming capabilities of the Bair Hugger, Hotline, Standard Ranger and Fluido devices were evaluated in the laboratory with gravity flow via a 14G cannula (1 m head of fluid) and with the fluid bag pressurised to 300 mmHg. The resulting flows (70-450 ml.min(-1)) were recorded. ⋯ However, the Standard Ranger with gravity flow and the Fluido with both gravity and pressurised flow achieved 35 degrees C, whereas the Bair Hugger and Hotline with both gravity and pressurised flow, and the Standard Ranger with pressurised flow, achieved only 24-31 degrees C. However, from the way delivered temperatures changed with flow, we calculated that all four devices would achieve close to 37 degrees C at the flows specified by the manufacturers: 17, 83, 150 and 800 ml.min(-1) for the Bair Hugger, Hotline, Standard Ranger and Fluido, respectively.