Anaesthesia
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We wished to investigate whether intensive care represents good value for money to the National Health Service in the UK using cost-effectiveness analysis. We developed a cost-effectiveness model using secondary data sources to estimate the incremental cost per quality adjusted life year gained of treatment in intensive care vs non-intensive care treatment in adults. Estimates of hospital mortality with and without intensive care were obtained from seven published studies and from data published by the Intensive Care National Audit and Research Centre. ⋯ This figure is sensitive to the mortality risk reduction associated with intensive care. Despite the high daily cost of intensive care, its cost-effectiveness is excellent and compares favourably with other commonly used health interventions. Our findings suggest that adult intensive care represents good value for money.
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This study was undertaken to investigate and calibrate the isoflurane output of an Oxford Miniature Vaporiser (OMV) draw-over vaporiser with reversed gas flows. Plenum or Boyles type machines have gas flowing left to right through the apparatus. Draw over anaesthesia systems, in contrast, traditionally have the carrier gas, air plus oxygen, flowing right to left through the vaporiser. ⋯ The predictable output of the OMV vaporiser assumes the correct direction of gas flows for the device. There are many second hand right to left OMV vaporisers for sale to developing countries where the nuances of vaporiser orientation add unnecessarily to the desired simplicity of anaesthesia. A simple calibration scale for reversed gas flows through the OMV vaporiser would be useful.
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Multicenter Study
The use of single-use devices in anaesthesia: balancing the risks to patient safety.
Single-use devices are designed, manufactured and sold to be used once and then discarded. This paper addresses growing concerns about the quality of some devices. ⋯ Interview data suggests that when choosing to use a single-use device, clinicians balance concerns about the risk of infection against those about the risk of injury. However, despite reservations about induced harm and the unknown risk of an iatrogenic disease, most clinicians would want single-use devices used on themselves and their family if they were patients.
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Randomized Controlled Trial Comparative Study
Bilateral intra-oral, infra-orbital nerve block for postoperative analgesia following cleft lip repair in paediatric patients: comparison of bupivacaine vs bupivacaine-pethidine combination.
This prospective, randomised, double blind study compared the efficacy of pethidine as an adjuvant to bupivacaine with the efficacy of bupivacaine alone for infra-orbital nerve block in alleviating postoperative pain in children undergoing cleft lip repair. Forty paediatric patients aged between 5 and 60 months undergoing cleft lip repair were randomly allocated to two groups of 20. ⋯ The median (IQR) duration of analgesia from the time of administration of block in group B was 18 h (14.2-20) compared to 29.1 h (24-36) in group P (p = 0.001). Addition of pethidine as an adjunct to local anaesthetic significantly prolonged the duration of postoperative analgesia without any adverse effects.