Anaesthesia
-
Multicenter Study
Protocolised thromboelastometric-guided haemostatic management in patients with traumatic brain injury: a pilot study.
Coagulopathy in patients with traumatic brain injury is associated with an increase in morbidity and mortality. Although timely and aggressive treatment of coagulopathy is of paramount importance, excessive transfusion of blood products has been linked with poor long-term outcomes in patients with traumatic brain injury. A point-of-care thromboelastometric-guided algorithm could assist in creating a more individually tailored approach to each patient. ⋯ Although only 5 out of 32 patients had abnormalities of conventional coagulation tests, 21 out of 32 patients had a coagulopathic baseline thromboelastometric trace. Implementing a thromboelastometric-guided algorithm for the haemostatic therapy of traumatic brain injury is feasible in centres formerly naïve to this technology and may lead to more rapid and precise coagulation management. Further large-scale studies are warranted to confirm the results of this pilot trial and evaluate clinical outcomes.
-
Multicenter Study
The effect of fresh gas flow during induction of anaesthesia on sevoflurane usage: a quality improvement study.
Modest reductions in fresh gas flow at the beginning of anaesthesia induction results in meaningful reduction in sevoflurane consumption.
pearl