American journal of respiratory and critical care medicine
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Am. J. Respir. Crit. Care Med. · Apr 2016
Multicenter StudyRhinovirus Detection in Symptomatic and Asymptomatic Children: Value of Host Transcriptome Analysis.
Rhinoviruses (RVs) are a major cause of symptomatic respiratory tract infection in all age groups. However, RVs can frequently be detected in asymptomatic individuals. ⋯ Symptomatic RV infection induced a robust and reproducible transcriptional signature, whereas identification of RV in asymptomatic children was not associated with significant systemic transcriptional immune responses. Transcriptional profiling represents a useful tool to discriminate between active infection and incidental virus detection.
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Am. J. Respir. Crit. Care Med. · Apr 2016
Multicenter Study Observational StudyCentral Sleep Disordered Breathing Predicts Incident Atrial Fibrillation in Older Males.
Although research supports a sleep-disordered breathing and atrial fibrillation association, prospective data examining sleep-disordered breathing predicting incident atrial fibrillation are lacking. ⋯ In older men, central apnea and Cheyne-Stokes respiration predicted increased atrial fibrillation risk, with findings being strongest in older participants in whom overall sleep-disordered breathing also increased atrial fibrillation risk.