Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology
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Ann. Allergy Asthma Immunol. · Jan 2011
Multicenter StudyPredictors of hospital admission for food-related allergic reactions that present to the emergency department.
guidelines do not provide specific hospitalization criteria for patients presenting to the emergency department (ED) with food-related allergic reactions. ⋯ most patients presenting to the ED with food-related allergic reactions are discharged. Several patient factors were independently associated with hospital admission in ED patients with food-related allergic reactions.
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Ann. Allergy Asthma Immunol. · Mar 2010
Randomized Controlled Trial Multicenter StudyEfficacy and safety of levocetirizine in improving symptoms and health-related quality of life in US adults with seasonal allergic rhinitis: a randomized, placebo-controlled study.
Levocetirizine, a second-generation antihistamine for symptomatic treatment of allergic rhinitis and chronic idiopathic urticaria, has not been previously studied in US patients. ⋯ Levocetirizine was well tolerated and was significantly more effective than placebo in improving the naso-ocular symptoms and health-related quality of life in US patients with SAR.
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Ann. Allergy Asthma Immunol. · Feb 2010
Randomized Controlled Trial Multicenter StudyA randomized, placebo-controlled study of intravenous montelukast in children with acute asthma.
Up to 30% of patients require hospitalization for acute asthma despite standard therapy in the emergency department. In adults, intravenous montelukast added to standard therapy significantly improved forced expiratory volume in 1 second (FEV1) and reduced hospital admissions compared with standard therapy alone. ⋯ In this study of children with acute asthma, intravenous montelukast was not significantly better than placebo in improving FEV1, symptoms, or overall hospital course.
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Ann. Allergy Asthma Immunol. · Jul 2009
Randomized Controlled Trial Multicenter StudyEfficacy and tolerability of once-daily budesonide/formoterol pressurized metered-dose inhaler in adults and adolescents with asthma previously stable with twice-daily budesonide/ formoterol dosing.
The goal of asthma therapy is to control symptoms using minimal pharmacologic intervention. ⋯ Pulmonary function and asthma control were more effectively maintained with all budesonide/formoterol regimens vs once-daily budesonide and with twice-daily budesonide/formoterol at twice the daily formoterol dose vs both once-daily budesonide/formoterol doses.
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Ann. Allergy Asthma Immunol. · Nov 2008
Randomized Controlled Trial Multicenter StudyPatient-reported outcomes in adults with moderate to severe asthma after use of budesonide and formoterol administered via 1 pressurized metered-dose inhaler.
Patient-reported outcomes (PROs) are important for evaluating asthma therapy. ⋯ Significantly greater improvements in health-related quality of life and asthma control and greater treatment satisfaction were observed with budesonide/formoterol pMDI vs placebo.