Annals of internal medicine
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Comment Meta Analysis
In older LTC residents, transitional care interventions vs. usual care reduce hospital readmissions.
Birtwell K, Planner C, Hodkinson A, et al. Transitional care interventions for older residents of long-term care facilities: a systematic review and meta-analysis. JAMA Netw Open. 2022;5:e2210192. 35507344.
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Comment Meta Analysis
In ischemic stroke, IV alteplase within 3 h of onset improves functional outcome vs. control.
Mun KT, Bonomo JB, Liebeskind DS, et al. Fragility index meta-analysis of randomized controlled trials shows highly robust evidential strength for benefit of < 3 hour intravenous alteplase. Stroke. 2022;53:2069-74. 35543129.
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Comment Meta Analysis
In type 2 diabetes, SGLT2 inhibitors reduced risk for serious hyperkalemia without increasing hypokalemia.
Neuen BL, Oshima M, Agarwal R, et al. Sodium-glucose cotransporter 2 inhibitors and risk of hyperkalemia in people with type 2 diabetes: a meta-analysis of individual participant data from randomized, controlled trials. Circulation. 2022;145:1460-70. 35394821.
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Comment Meta Analysis
In older adults discharged from hospital, home-based exercise programs improve some outcomes.
Lin I, Glinsky J, Dean C, et al. Effectiveness of home-based exercise for improving physical activity, quality of life and function in older adults after hospitalisation: a systematic review and meta-analysis. Clin Rehabil. 2022;36:1170-85. 35522200.