Annals of internal medicine

• Latest
• Best
• Search…

• Ann. Intern. Med. · Sep 2022

  Comment Meta Analysis

  In ischemic stroke, IV alteplase within 3 h of onset improves functional outcome vs. control.

  Mun KT, Bonomo JB, Liebeskind DS, et al. Fragility index meta-analysis of randomized controlled trials shows highly robust evidential strength for benefit of < 3 hour intravenous alteplase. Stroke. 2022;53:2069-74. 35543129.

  keep reading… or not…

• Ann. Intern. Med. · Sep 2022

  Comment Meta Analysis

  In older LTC residents, transitional care interventions vs. usual care reduce hospital readmissions.

  Birtwell K, Planner C, Hodkinson A, et al. Transitional care interventions for older residents of long-term care facilities: a systematic review and meta-analysis. JAMA Netw Open. 2022;5:e2210192. 35507344.

  read on… or not…

• Ann. Intern. Med. · Sep 2022

  Comment Meta Analysis

  In older adults discharged from hospital, home-based exercise programs improve some outcomes.

  Lin I, Glinsky J, Dean C, et al. Effectiveness of home-based exercise for improving physical activity, quality of life and function in older adults after hospitalisation: a systematic review and meta-analysis. Clin Rehabil. 2022;36:1170-85. 35522200.

  expand abstract… or not…

• Ann. Intern. Med. · Sep 2022

  Comment Meta Analysis

  In type 2 diabetes, SGLT2 inhibitors reduced risk for serious hyperkalemia without increasing hypokalemia.

  Neuen BL, Oshima M, Agarwal R, et al. Sodium-glucose cotransporter 2 inhibitors and risk of hyperkalemia in people with type 2 diabetes: a meta-analysis of individual participant data from randomized, controlled trials. Circulation. 2022;145:1460-70. 35394821.

  expand abstract… or not…