Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Jul 2020
Randomized Controlled TrialTranscranial Pulsed Ultrasound with Alteplase Intravenous Thrombolysis for Vascular Recanalisation in Acute Ischemic Stroke.
The objective of study was to investigate the effect of transcranial pulsed ultrasound combined with alteplase on treatment of vascular recanalisation in acute ischemic stroke patients. Eighty-two patients were randomly divided equally into two groups. Group A was treated with transcranial pulsed ultrasound combined with alteplase intravenous thrombolysis. ⋯ At 90 days after treatment, rate of favourable prognosis [(modified rankin scale (mRS) ≤2 points)] of group A was higher than that of group B (p=0.001). Transcranial pulsed ultrasound combined with alteplase intravenous thrombolytic treatment can improve vascular recanalization rate and prognosis. Key Words: Transcranial pulsed ultrasound, Acute ischemic stroke, Alteplase, Thrombolysis, Vascular recanalisation.