Journal of evaluation in clinical practice
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Multicenter Study
Modelling survival in acute severe illness: Cox versus accelerated failure time models.
The Cox model has been the mainstay of survival analysis in the critically ill and time-dependent covariates have infrequently been incorporated into survival analysis. ⋯ Time dependence of predictors of survival in ALI/ARDS exists and must be appropriately modelled. The Cox model with time-varying covariates remains a flexible model in survival analysis of patients with acute severe illness.