British journal of anaesthesia
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Mid-latency somatosensory evoked responses are used to monitor the integrity of the sensory pathways intra-operatively. They can quantify the effects of anaesthetics on the central nervous system. Mid-latency auditory evoked responses have been related to cognition during anaesthesia, but there are no detailed studies using median nerve somatosensory evoked responses (MnSSER). ⋯ We conclude that MnSSER components warrant further investigation for studying the effects of anaesthetic drugs on cognitive function.
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Comparative Study
Phonomyography of the corrugator supercilii muscle: signal characteristics, best recording site and comparison with acceleromyography.
This study investigated the acoustic signal characteristics and best recording site of phonomyography at the corrugator supercilii muscle and compared phonomyography with acceleromyography. ⋯ Phonomyography can be used to determine neuromuscular block at the corrugator supercilii muscle. In comparison with acceleromyography, phonomyography tends to measure a longer onset with more pronounced maximum effect and shorter recovery of neuromuscular block.
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Randomized Controlled Trial Comparative Study Clinical Trial
Effects of remifentanil and alfentanil on the cardiovascular responses to induction of anaesthesia and tracheal intubation in the elderly.
We compared the effects of remifentanil and alfentanil on arterial pressure and heart rate at induction of anaesthesia and tracheal intubation in 40 ASA I-III patients aged greater than 65 yr, in a randomized double-blind study. ⋯ Remifentanil and alfentanil similarly attenuate the pressor response to laryngoscopy and intubation, but the incidence of hypotension confirms that both drugs should be used with caution in elderly patients.
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Randomized Controlled Trial Comparative Study Clinical Trial
Remifentanil by patient-controlled analgesia compared with intramuscular meperidine for pain relief in labour.
The pharmacokinetics of remifentanil suggests that it may be suitable for analgesia during labour. ⋯ In this pilot study, remifentanil by PCA gave better pain relief to mothers in labour than intramuscular meperidine. However, remifentanil is a potent respiratory depressant and adequate continuous monitoring is necessary.