British journal of anaesthesia
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Randomized Controlled Trial
Influence of Bayesian optimization on the performance of propofol target-controlled infusion.
Target controlled infusion (TCI) systems use population-based pharmacokinetic (PK) models that do not take into account inter-individual residual variation. This study compares the bias and inaccuracy of a population-based vs a personalized TCI propofol titration using Bayesian adaptation. Haemodynamic and hypnotic stability, and the prediction probability of alternative PK models, was studied. ⋯ Dutch Trial Registry NTR4518.
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Randomized Controlled Trial
Gastric emptying for liquids of different compositions in children.
Pre-operative fasting balances safety against patient discomfort. We compared the gastric emptying profiles of a novel clear, high protein drink against a "traditional" clear and a non-clear fluid. ⋯ clinicaltrials.gov NCT02938065 clinicaltrials.gov/ct2/show/NCT02938065.
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Randomized Controlled Trial
Effect of gum chewing on gastric volume and emptying: a prospective randomized crossover study.
Current fasting guidelines allow oral intake of water up to 2 h before induction of anaesthesia. We assessed whether gum chewing affects gastric emptying of 250 ml water and residual gastric fluid volume measured 2 h after ingestion of water. ⋯ NCT02673307.
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Randomized Controlled Trial Multicenter Study
Cost-effectiveness of a systematic e-assessed follow-up of postoperative recovery after day surgery: a multicentre randomized trial.
Most surgeries are done on a day-stay basis. Recovery assessment by phone points (RAPP) is a smartphone-based application (app) to evaluate patients after day surgery. The aim of this study was to estimate the cost-effectiveness of using RAPP for follow-up on postoperative recovery compared with standard care. ⋯ NCT02492191.
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Randomized Controlled Trial Multicenter Study
Evaluation of postoperative recovery in day surgery patients using a mobile phone application: a multicentre randomized trial.
Many patients undergoing anaesthesia and surgery experience postoperative complications. Our aim was to investigate whether a systematic follow-up smartphone-based assessment, using recovery assessment by phone points (RAPP) compared with standard care, had a positive effect on day surgery patients' postoperative recovery. We also investigated whether there were differences in women and men's recovery and recovery scores. ⋯ NCT02492191.