International journal of clinical practice
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Int. J. Clin. Pract. · Oct 2007
Randomized Controlled TrialThe suppression of gastro-oesophageal reflux by alginates.
The aim of this study was to compare alginate products with the same amount of active ingredients but different dosage forms, in the suppression of reflux provoked by a standard meal in healthy human volunteers, using ambulatory oesophageal pH monitoring. ⋯ The study shows that alginate reflux suppressants containing a low amount of antacid are effective in suppressing acid reflux and that suspension and tablet forms are able to give equivalent acid suppression.