International journal of clinical practice
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Int. J. Clin. Pract. · Jun 2021
Randomized Controlled TrialComparison of Losartan and Amlodipine Effects on the Outcomes of Patient with COVID-19 and Primary Hypertension: A Randomized Clinical Trial.
Controversy exists regarding the drug selection in hypertension (HTN) management in patients with COVID-19. This study aimed to compare the effects of losartan and amlodipine in patients with primary HTN and COVID-19. ⋯ There was no priority in losartan or amlodipine administration in COVID-19 patients with primary HTN in decreasing mortality rate, hospital and ICU length stay. Further studies need to clarify the first-line anti-HTN medications in COVID-19.
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Int. J. Clin. Pract. · Jun 2021
Seroprevalence of rubella virus among pregnant women: A 4-year registered based study from Family medicine and Obstetric clinics in Saudi Arabia.
This study aimed to determine rubella virus infectivity and immune status in pregnant females who visited the family medicine and obstetrics clinics at a large hospital in Saudi Arabia, and to identify the possible predictors of rubella susceptibility. ⋯ Approximately 24% of pregnant were susceptible to rubella virus infections in this study. Screening females of child-bearing age and reimmunisation of susceptible cases before pregnancy are suggested. Further studies to investigate the impact of applying this policy in premarital screening are recommended.
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Int. J. Clin. Pract. · Jun 2021
The association between dietary acid load with cardiometabolic risk factors and inflammatory markers among elderly men: A cross-sectional study.
Existing epidemiological data on dietary acid load and cardiovascular disease (CVD) are controversial. There is no literature evaluating the association between dietary acid load (DAL) with cardiometabolic risk factors and inflammatory markers in elderly. ⋯ Men with higher DAL scores had a higher risk of MetS, hypertriglyceridemia and LAP. Our findings suggest that further prospective studies are required to appraise DAL-CVD risk factors in populations with varying dietary patterns.
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Int. J. Clin. Pract. · Jun 2021
Evaluation of Epidemiology, Clinical Display, Prognosis, Diagnosis and Treatment in Patients with COVID-19.
COVID-19 is considered a widespread concern in global public health. Diagnoses of COVID-19 in some cases are necessary because of severe prognosis. In this study, epidemiologies, clinical and demographic characteristics of patients with COVID-19 were studied in Taleghani Hospital, Urmia, Iran. ⋯ COVID-19 involves different organs of the body with different severity. In the meantime, smoking was not a risk factor for the virus or associated with severe manifestations of the disease. Patients with high creatinine and CPK, pulmonary involvement above 25%, and hypoxemia had a higher mortality rate. Increase of Spo2 by 1% can improve the patients by 24%. The results indicated that Kaletra had the most highest effect on improvement following COVID-19.
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Int. J. Clin. Pract. · Jun 2021
Potential Drug-Drug Interactions with Psychotropic Drugs in Pediatric Inpatients: A Cross-Sectional Study.
Polypharmacy and drug-drug interactions (DDIs) are important problems that necessitate more attention in paediatric inpatients. This study aimed to determine and evaluate DDIs in paediatric inpatients using psychotropic drugs. ⋯ Psychotropic drug-related DDI is a major problem in the paediatric population and the clinical significance of the potential DDIs' risk should be determined in patient-centred care and managed by the multidisciplinary team.