The British journal of surgery
-
Multicenter Study Comparative Study Observational Study
Mortality of emergency abdominal surgery in high-, middle- and low-income countries.
Surgical mortality data are collected routinely in high-income countries, yet virtually no low- or middle-income countries have outcome surveillance in place. The aim was prospectively to collect worldwide mortality data following emergency abdominal surgery, comparing findings across countries with a low, middle or high Human Development Index (HDI). ⋯ NCT02179112 (http://www.clinicaltrials.gov).
-
Randomized Controlled Trial Multicenter Study
Quality of life from a randomized trial of open and endovascular repair for abdominal aortic aneurysm.
Long-term survival is similar after open or endovascular repair of abdominal aortic aneurysm. Few data exist on the effect of either procedure on long-term health-related quality of life (HRQoL) and health status. ⋯ In this study EVAR appeared to be associated with less severe disruption to HRQoL and health status in the short term. However, during longer-term follow-up to 5 years, patients receiving open repair appeared to have improved quality of life and health status.
-
Multicenter Study Observational Study
Multicentre observational study of outcomes after drainage of acute perianal abscess.
Management of perianal abscesses has remained largely unchanged for over 50 years. The evidence for postoperative wound packing is limited and may expose patients to painful procedures with no clinical benefit and at considerable increased cost. ⋯ Recurrent abscess is rare and fistula occurs in one-quarter of the patients. Packing is painful and costly.
-
Radiation-induced fibrosis (RIF) is a late complication of radiotherapy that results in progressive functional and cosmetic impairment. Autologous fat has emerged as an option for soft tissue reconstruction. There are also sporadic reports suggesting regression of fibrosis following regional lipotransfer. This systematic review aimed to identify cellular mechanisms driving RIF, and the potential role of lipotransfer in attenuating these processes. ⋯ Understanding how lipotransfer causes regression of RIF remains unclear; there are a number of new hypotheses for future research.