Neuromodulation : journal of the International Neuromodulation Society
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Randomized Controlled Trial
Enhancement of affective processing induced by bifrontal transcranial direct current stimulation in patients with major depression.
Our aim was to evaluate whether one single section of transcranial direct current stimulation (tDCS), a neuromodulatory technique that noninvasively modifies cortical excitability, could induce acute changes in the negative attentional bias in patients with major depression. ⋯ Active but not sham tDCS significantly modified the negative attentional bias. These findings add evidence that a single tDCS session transiently induces potent changes in affective processing, which might be one of the mechanisms of tDCS underlying mood changes.