J Trauma
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Blunt cerebrovascular injury (BCVI) carries a high morbidity and mortality, especially when diagnosis is delayed. Recent studies have shown that increased recognition of these injuries is achieved with prompt screening, allowing for early treatment and better outcome. Controversy still exists, however, on the best screening test. This study was used to evaluate the role of helical computed tomographic angiography (CTA) of the carotid and vertebral arteries in the early screening of BCVI. ⋯ CTA is an excellent test with which to screen for BCVI.
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This study was performed to assess the effect of poly-N-acetyl glucosamine fiber slurry on plasma clotting proteins, platelets, and red blood cells in the clotting of the blood. ⋯ Poly-N-acetyl glucosamine slurry activates platelets.
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This study tests whether the hemostatic action of poly-N-acetyl glucosamine (p-GlcNAc) fiber material involves vasoconstrictor release leading to closure of an aortic laceration. ⋯ The mechanism of hemostasis by poly-N-acetyl glucosamine involves endothelin release independent of formed elements of blood.
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Comparative Study
Application of the poly-N-acetyl glucosamine-derived rapid deployment hemostat trauma dressing in severe/lethal Swine hemorrhage trauma models.
The Rapid Deployment Hemostat (RDH) Bandage was developed for the rapid control of bleeding caused by trauma. ⋯ The RDH Bandage was superior to a commercially available fibrin bandage in controlling hemorrhage, decreasing blood loss, and increasing survival.
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General mediastinal width, left mediastinal width, and mediastinal width ratio were compared as radiographic predictors of aortic injury. ⋯ Both an LMW of 6 cm or more and an MWR of 0.60 or more are better radiographic criteria than an MW of 8 cm or more for predicting blunt aortic injury. Trauma patients with positive test results based on the combined LMW and MWR criteria should proceed immediately to aortography or helical computed tomography.