Ulus Travma Acil Cer
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Ulus Travma Acil Cer · Feb 2023
A comparative study of digital nerve and digital arterial repairs performed using running versus interrupted suture techniques in finger replantations.
The present study aimed to retrospectively analyze replantations and compared the success rates of different suturing techniques. ⋯ Finger replantation is a difficult-to-perform surgical procedure requiring consideration of the surgical indications and the presence of an experienced surgical team. Regardless of the suture technique in finger amputations, performing venous anastomosis after arterial anastomosis is essential to restore circulation.
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Ulus Travma Acil Cer · Feb 2023
Case ReportsOut-of-hospital cardiac arrest due to cervical spine injury by uncertain trauma: A study of two cases.
Cervical spinal cord injury is a well-known cause of cardiac arrest in trauma victims. Unless trauma is definitively suspected, emergency medical services teams perform resuscitation in the pre-hospital stage without cervical spine immobilization. During advanced cardiovascular life support (ACLS), intubation with cervical spinal immobilization causes difficulty in accessing the airway, thus, immobilization tends to not be performed, unless the patient is a clear case of trauma. ⋯ Emergency medical physicians tend to neglect cervical spine injury when the likelihood of trauma is unclear in a patient presenting with OHCA. These cases urge physicians to consider the possibility of cervical spinal injuries, even in cases of minor trauma. If there is a possibility of cervical spinal injury, imaging should not be delayed and should be followed by appropriate treatment.
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Ulus Travma Acil Cer · Feb 2023
Histopathological efficacy of tacrolimus in an experimental head trauma study.
This study aimed to investigate the protective effect of tacrolimus (FK506), an immunosuppressive agent, on secondary brain damage in rats with experimental head trauma. ⋯ It was observed that the group treated with FK506 had a statistically significant increase in gliosis in the traumatic area compared to the other control groups. This shows that FK506 cannot prevent and even increase gliosis by a mechanism that has not yet been clarified. In conclusion, it is obvious that the FK506 immunosuppressive agent does not reduce post-traumatic brain injury; on the contrary, it increases gliosis.
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Ulus Travma Acil Cer · Feb 2023
Histopathological investigation of the effect of chitosan on oral mucous wound healing in experimentally established diabetic rats.
In our study, it was aimed to histopathologically investigate the effects of chitosan on wound healing in the oral mucosa by applying the gel form of experimentally induced diabetes mellitus. ⋯ It was observed that chitosan did not cause foreign body reaction in any of the groups on the 2nd and 5th days.
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Ulus Travma Acil Cer · Feb 2023
The determination of the protective role of sildenafil administration in rats with sepsis-induced liver injury.
Sepsis is a complex syndrome which comes out after infection, characterized by activation of inflammation and infection and has a high morbidity and mortality. Sildenafil (SLD) is a selective phosphodiesterase Type 5 enzyme inhibitor and is used in the treatment of erectile dysfunction effectively all over the world. In this study, we investigated whether SLD had protective effect or not by studying the effect of SLD on reactive oxygen species and antioxidants in cecal ligation and puncture (CLP) polymicrobial sepsis model in rat liver histopathologically and biochemically. ⋯ It was shown that acute SLD administration decreased liver damage in septic rats dose-dependently in this study. In addition, it was observed that it corrected the broken oxidant-antioxidant balance. This might mediate the protective effect of SLD in liver. However, we believe that new experimental and clinical studies should be in the future to understand the protective effect of SLD in liver.