World Neurosurg
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Comparative Study
Comparison of Minimally Invasive and Pterional Craniotomies for Ruptured Anterior Circulation Aneurysms: A Propensity Score-Matched Analysis.
Minimally invasive craniotomy (MIC) for ruptured aneurysm remains a debatable issue because of unclear information regarding its safety and efficacy compared with standard approaches. Here, we compared the outcomes between MIC and pterional craniotomy (PTC) for the treatment of ruptured anterior circulation aneurysms. ⋯ For the treatment of ruptured anterior circulation aneurysms, MIC was comparable with PTC and presented additional advantage in terms of earlier recovery. Therefore, MIC can be considered an alternative surgical treatment in this setting.
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Atlantoaxial fusion procedures may be difficult in situations such as high-riding vertebral artery, a narrow C2 pedicle, and the presence of ponticulus posticus-arcuate foramen. With respect to vertebral artery (VA) anomalies, persistent first intersegmental artery, extracranial origin of the posterior inferior cerebellar artery at the C1-C2 level, and fenestration of the VA are all major risk factors for VA injury in C1-C2 fusion surgeries. ⋯ We combined a unilateral transarticular screw and modified Brook's procedure with sublaminar tapping for additional augmentation of fusion. We would like to highlight this C1 posterior arch screw as an alternative procedure for atlantoaxial fusion.
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This study bioinformatically analyzed aberrant genes and pathways for associations with glioblastoma development and prognosis. ⋯ This study showed several DEGs in glioblastoma, and aberrant expression of their hub genes was associated with glioblastoma pathogenesis and poor prognosis, especially the signaling axes of TAF7/CCNB1, TAF7/CCNA2, and GTF2E2/CDC20.