World Neurosurg
-
To investigate intellectual development after functional hemispherectomy and to evaluate the favorable or unfavorable factors affecting prognosis. ⋯ Successful functional hemispherectomy significantly improved the cognitive function of patients. Functional hemispherectomy is a safe and effective treatment for patients with intractable epilepsy caused by hemispheric lesions and can effectively promote intellectual recovery and development.
-
Moyamoya syndrome, a progressive, idiopathic stenosis of the internal carotid arteries, results in increased risk for both ischemic and hemorrhagic strokes. Revascularization procedures have been shown in small studies to be both safe and efficacious for these patients; however, randomized controlled trials are lacking. The goal of this systematic review is to organize the literature evaluating surgical intervention versus conservative medical management. ⋯ We present a large systematic review of the literature regarding outcomes of surgical and medical management for patients with moyamoya syndrome and sickle cell disease. The findings redemonstrate the efficacy and safety of surgical revascularization, and advocate for earlier discussion around surgical intervention.