World Neurosurg
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Review Meta Analysis
Effectiveness of Sealants in Prevention of CSF Leakage after Spine Surgery: a Systematic Review.
Sealants are often used in spine surgery to prevent postoperative cerebrospinal fluid (CSF) leakage. ⋯ Currently available sealants seem not to reduce the rate of CSF leakage in spine surgery. In endoscopic and minimally invasive surgery, the CSF leakage rate is less frequent compared with open, conventional surgery regardless of sealant use.
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Review Meta Analysis
Does tranexamic acid improve bleeding, transfusion, and hemoglobin level in patients undergoing multi-level spine surgery? A systematic review and meta-analysis.
To investigate the influence of tranexamic acid (TXA) on blood loss and blood transfusion in multiple-level spine surgery and evaluate whether hemoglobin and platelet levels are altered as a result. ⋯ The application of TXA can effectively reduce intraoperative blood loss and perioperative blood transfusion in patients undergoing multiple-level spine surgery, and it can restore hemoglobin levels after surgery.
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There are some controversies about the surgical treatment strategy of mirror aneurysms. Whether to choose 1-stage or 2-stage surgery, bilateral or unilateral craniotomy, or surgical or interventional treatment are the main points in dispute. In this review, the different surgery strategies faced by patients are discussed. ⋯ The 3D Slicer can help surgeons undertake adequate preoperative preparation. In addition, we also introduce some ruptured factors (e.g., age, gender, hypertension, morphologic, and hemodynamic) concerning mirror aneurysm. Systematic discussion of the controversies and methods in surgical treatment of mirror aneurysms may provide new perspectives in future research for the prevention and treatment of mirror aneurysms.
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Review Case Reports
Pial arteriovenous fistula with multiple venous aneurysms resembling a vein of Galen aneurysmal malformation.
Pial arteriovenous fistulas are abnormal vascular connections between arteries and the cranial venous system on the surface of the brain in the pia mater. In contrast to vein of Galen aneurysmal malformations, they lack a true vascular nidus and may only indirectly involve the vein of Galen. ⋯ If cerebral venous dilations are encountered, one must keep in mind that the location of the fistula may not be in close proximity to the dilated veins, especially when there is a suspicion for vein of Galen aneurysmal malformation. Other pathologies, such as pial arteriovenous fistula, in a region away from the site of the vein of Galen must be considered.
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Review Case Reports
Morphologic changes after denosumab therapy in patients with giant cell tumor of the spine: Report of four cases and a review of the literature.
To evaluate the quantitative, radiologic, morphologic, and histologic effects of neoadjuvant denosumab treatment (DT) on 4 patients with spinal giant cell tumor of bone (GCTB) and determine the tumor shrinkage effects of DT for spinal GCTB. ⋯ In all patients, osteolytic tumor volume decreased after DT. This tumor shrinkage effect of DT may increase the mechanical stress on the thin cortical rim, leading to the acute collapse of the affected vertebral body if it consists mostly of osteolytic lesions. The presence of adequate anterior cortical bone could prevent acute vertebral collapse after DT.