World Neurosurg
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Review Meta Analysis
The relationship between modic changes and endplate sclerosis in patients with lumbar degenerative disease: A systematic review and network meta-analysis.
To explore the relationship between modic changes (MCs) and endplate sclerosis in patients with lumbar degenerative disease. ⋯ Endplate sclerosis occurs in all kinds of MCs. With increasing grade of MCs, the incidence of endplate sclerosis gradually increased. The endplate sclerosis rate in mixed-type MCs was significantly greater than that in MC2 and significantly lower than that in MC3. The endplate sclerosis rate in the mixed-type, including MC3 (MC1/3 and MC2/3), was significantly greater than that in the MC1/2.
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Review Meta Analysis
Posterior pedicle screw fixation with indirect decompression versus direct decompression in treating thoracolumbar burst fracture: A systematic review and meta-analysis.
To compare the safety and efficacy between posterior pedicle screw fixation with direct versus indirect decompression in treating patients with thoracolumbar burst fracture. ⋯ Posterior pedicle screw fixation with indirect decompression was safe and effective for thoracolumbar burst fracture with or without neurologic deficits when posterior longitudinal ligament was intact.
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Review Meta Analysis
Gene Therapy and Spinal Fusion: Systematic Review and Meta-analysis of the Available Data.
To analyze the extant literature describing the application of gene therapy to spinal fusion. ⋯ Gene therapy may augment spinal fusion; however, future investigation in clinical populations is necessary.
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This retrospective study aimed to determine the Japanese Orthopedic Association Back Pain Evaluation Questionnaire (JOABPEQ) cutoff scores for assessing patient satisfaction postlateral lumbar interbody fusion (LLIF) in degenerative lumbar spinal stenosis (DLSS) patients. ⋯ This study underscores the value of patient-centered outcomes in evaluating LLIF surgery success for DLSS. The identified JOABPEQ cutoff values provide a quantitative tool for assessing patient satisfaction, emphasizing the necessity of comprehensive postoperative evaluations beyond traditional clinical metrics for improved patient care and life quality.
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Socioeconomic status (SES) is a major determinant of quality of life and outcomes. However, SES remains difficult to measure comprehensively. Distress communities index (DCI), a composite of 7 socioeconomic factors, has been increasingly recognized for its correlation with poor outcomes. As a result, the objective of the present study is to determine the predictive value of the DCI on outcomes following intracranial tumor surgery. ⋯ Intracranial tumor patients from distressed communities are at increased risk for adverse events and death in the postoperative period. DCI may be a useful, holistic measure of SES that can help risk stratifying patients and should be considered when building healthcare pathways.