The Journal of clinical endocrinology and metabolism
The most recent articles from:
May 2013
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J. Clin. Endocrinol. Metab. · May 2013
Multicenter StudyThe relationship between vitamin D status and adrenal insufficiency in critically ill children.
Recent studies in critically ill populations have suggested both adrenal insufficiency (AI) and vitamin D deficiency to be associated with worse clinical outcome. There are multiple mechanisms through which these pleiotropic hormones might synergistically influence critical illness. ⋯ We did not find evidence of a direct association between vitamin D status and critical illness-related AI. However, our results do suggest that vitamin D deficiency exacerbates the effect of AI on cardiovascular stability in critically ill children.