The Journal of clinical endocrinology and metabolism
The most recent articles from: October 2015
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J. Clin. Endocrinol. Metab. · Oct 2015
Randomized Controlled Trial Multicenter StudySteroid Sex Hormones, Sex Hormone-Binding Globulin, and Diabetes Incidence in the Diabetes Prevention Program.
Steroid sex hormones and SHBG may modify metabolism and diabetes risk, with implications for sex-specific diabetes risk and effects of prevention interventions. ⋯ Estrogens and T predicted diabetes risk in men but not in women. SHBG and its polymorphisms did not predict risk in men or women. Diabetes risk is more potently determined by obesity and glycemia than by sex hormones.