The Journal of pediatrics
-
The Journal of pediatrics · Jul 2013
Randomized Controlled TrialQuantitative end-tidal carbon dioxide monitoring in the delivery room: a randomized controlled trial.
To investigate the utility of continuous quantitative end-tidal CO2 (Etco2) monitoring for managing assisted ventilation in the delivery room (DR). ⋯ Etco2 monitoring in the DR did not reduce the proportion of admission Pco2 levels outside of the prespecified range in a population of infants supported mostly with noninvasive ventilation.
-
The Journal of pediatrics · Jul 2013
Randomized Controlled TrialOral sucrose for heel lance increases adenosine triphosphate use and oxidative stress in preterm neonates.
To examine the effects of sucrose on pain and biochemical markers of adenosine triphosphate (ATP) degradation and oxidative stress in preterm neonates experiencing a clinically required heel lance. ⋯ A single dose of oral sucrose, given before heel lance, significantly increased ATP use and oxidative stress in premature neonates. Because neonates are given multiple doses of sucrose per day, randomized trials are needed to examine the effects of repeated sucrose administration on ATP degradation, oxidative stress, and cell injury.
-
The Journal of pediatrics · Jul 2013
Randomized Controlled Trial Multicenter StudyThe NOFLO trial: low-flow nasal prongs therapy in weaning nasal continuous positive airway pressure in preterm infants.
To determine if low-flow nasal prongs therapy with room air, compared with no treatment, facilitates weaning from nasal continuous positive airway pressure (NCPAP) in very low birth weight (VLBW, birth weight <1500 g) infants. ⋯ In this study, we did not demonstrate a benefit of low-flow room air via nasal prongs to wean VLBW infants from NCPAP.