The Journal of pediatrics
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The Journal of pediatrics · Aug 2013
ReviewMedication-related emergency department visits and hospital admissions in pediatric patients: a qualitative systematic review.
To review and describe the current literature pertaining to the incidence, classification, severity, preventability, and impact of medication-related emergency department (ED) and hospital admissions in pediatric patients. ⋯ Medication-related ED visits and hospital admissions are common in pediatric patients, many of which are preventable. These ADEs result in significant healthcare utilization.
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The Journal of pediatrics · Aug 2013
Multicenter StudyBereaved parents' intentions and suggestions about research autopsies in children with lethal brain tumors.
To determine bereaved parents' perceptions about participating in autopsy-related research and to elucidate their suggestions about how to improve the process. ⋯ Because autopsy can help advance scientific understanding of the disease itself and because parents reported having no regret and even cited benefits, researchers should be encouraged to continue autopsy-related research. Parental perceptions about such studies should be evaluated in other types of pediatric diseases.
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The Journal of pediatrics · Aug 2013
Case ReportsSimultaneous colonic adenocarcinoma and medulloblastoma in a 12-year-old with biallelic deletions in PMS2.
We describe a 12-year-old girl, simultaneously presenting with colonic adenocarcinoma and medulloblastoma from bialleic deletions in the mismatch repair gene PMS2. Her distinctive physical and clinical findings are characteristic of constitutional mismatch repair deficiency syndrome. Earlier recognition of such findings may permit better screening and more effective treatment.
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The Journal of pediatrics · Aug 2013
Spontaneous intracranial hypotension in childhood and adolescence.
To describe the clinical and radiographic manifestations of spontaneous intracranial hypotension, a rarely diagnosed cause of headache in children. ⋯ Spontaneous intracranial hypotension in childhood is rare. Most patients can be treated effectively using a combination of epidural blood patching and percutaneous injections of fibrin glue or surgical CSF leak repair in refractory cases.
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The Journal of pediatrics · Aug 2013
Case ReportsDedicated retinal examination in children evaluated for physical abuse without radiographically identified traumatic brain injury.
To determine the rate of retinal hemorrhages in children evaluated for physical abuse without traumatic brain injury (TBI) by diagnostic imaging. ⋯ Forensically significant retinal hemorrhages are unlikely to be found in children evaluated for physical abuse without TBI on neuroimaging, and such children may not require routine dedicated retinal examination.