The Journal of pediatrics
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The Journal of pediatrics · Feb 2014
Multicenter StudyElectrographic seizures after convulsive status epilepticus in children and young adults: a retrospective multicenter study.
To describe the prevalence, characteristics, and predictors of electrographic seizures after convulsive status epilepticus (CSE). ⋯ After CSE, one-third of children who underwent EEG monitoring experienced electrographic seizures, and among these, one-third experienced entirely electrographic-only seizures. A previous diagnosis of epilepsy and the presence of interictal epileptiform discharges were risk factors for electrographic seizures.
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The Journal of pediatrics · Jan 2014
Randomized Controlled Trial Multicenter Study Comparative StudyMood disorders after traumatic brain injury in adolescents and young adults: a nationwide population-based cohort study.
To delineate the relationship between traumatic brain injury (TBI) and mood disorders from population-based data in Taiwan. ⋯ Our findings show a higher likelihood of manifesting mood disorders in adolescents and young adults who sustained a prior TBI. Health professionals should carefully monitor both the physical and psychological impacts of head trauma.
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The Journal of pediatrics · Dec 2013
Multicenter StudyVariability in the implementation of rapid response teams at academic American pediatric hospitals.
Pediatric rapid response teams have become standard over the past decade, but are organized heterogeneously at US academic hospitals, with rare financial support. To compare rapid response team efficacy, pediatric hospitals should agree on standard outcome measures, whether it be a standard definition of floor arrest or of clinical deterioration.
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The Journal of pediatrics · Dec 2013
Multicenter StudyTiming of interventions in the delivery room: does reality compare with neonatal resuscitation guidelines?
To determine the proportion of infants who had the tasks recommended in the neonatal resuscitation guidelines performed within 30 and 60 seconds of birth, and the time taken to perform each task. ⋯ Most newborns were not managed within the time frame recommended in resuscitation guidelines. The recommended 30- and 60-second intervals may be too short.
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The Journal of pediatrics · Nov 2013
Multicenter StudyAntithrombin concentrate use in children: a multicenter cohort study.
To describe the off-label use of antithrombin concentrate in tertiary care pediatric hospitals across the US. ⋯ The off-label use of antithrombin concentrate is increasing rapidly, particularly in critically ill children receiving extracorporeal membrane oxygenation, with few parallel studies to substantiate its safety or efficacy. Further preclinical and controlled clinical studies are critical to expanding our knowledge of this drug. In the meantime, antithrombin concentrate should be used judiciously by clinicians and following guidelines instated by hospitals.