The Journal of pediatrics
-
The Journal of pediatrics · May 2015
Randomized Controlled TrialEndotracheal Suction for Nonvigorous Neonates Born through Meconium Stained Amniotic Fluid: A Randomized Controlled Trial.
To assess whether endotracheal suctioning of nonvigorous infants born through meconium stained amniotic fluid (MSAF) reduces the risk and complications of meconium aspiration syndrome (MAS). ⋯ The current practice of routine endotracheal suctioning for nonvigorous neonates born through MSAF should be further evaluated.
-
The Journal of pediatrics · Apr 2015
Randomized Controlled TrialVasopressin versus dopamine for treatment of hypotension in extremely low birth weight infants: a randomized, blinded pilot study.
To evaluate vasopressin vs dopamine as initial therapy in extremely low birth weight (ELBW) infants with hypotension during the first 24 hours of life. ⋯ Vasopressin in ELBW infants as the initial agent for early hypotension appeared safe. This pilot study supports a larger randomized controlled trial of vasopressin vs dopamine therapy in ELBW infants with hypotension.
-
The Journal of pediatrics · Apr 2015
Randomized Controlled Trial Multicenter StudyA randomized clinical trial of therapeutic hypothermia mode during transport for neonatal encephalopathy.
To determine if temperature regulation is improved during neonatal transport using a servo-regulated cooling device when compared with standard practice. ⋯ Cooling using a servo-regulated device provides more predictable temperature management during neonatal transport than does usual care for outborn newborns with neonatal encephalopathy.
-
The Journal of pediatrics · Mar 2015
Randomized Controlled Trial Multicenter Study Observational StudySevere obesity and comorbid condition impact on the weight-related quality of life of the adolescent patient.
To assess links between comorbid health status, severe excess weight, and weight-related quality of life (WRQOL) in adolescents with severe obesity and undergoing weight-loss surgery (WLS) to inform clinical care. ⋯ WRQOL impairment is substantial for adolescents with severe obesity undergoing WLS, with predictors varying by sex. These patient-data highlight targets for education, support, and adjunctive care referrals before WLS. Furthermore, they provide a comprehensive empirical base for understanding heterogeneity in adolescent WRQOL outcomes after WLS, as weight and comorbidity profiles change over time.
-
The Journal of pediatrics · Feb 2015
Randomized Controlled Trial Multicenter StudyMulticenter randomized controlled trial of inhaled nitric oxide for pediatric acute respiratory distress syndrome.
To test the hypothesis that inhaled nitric oxide (iNO) would lead to improved oxygenation and a decrease in duration of mechanical ventilation in pediatric patients with acute respiratory distress syndrome. ⋯ The use of iNO was associated with a significantly reduced duration of mechanical ventilation and significantly greater rate of extracorporeal membrane oxygenation-free survival.