The Journal of surgical research
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Randomized Controlled Trial Comparative Study
Comparison of surgical outcomes between papillary thyroid cancer patients treated with the Harmonic ACE scalpel and LigaSure Precise instrument during conventional thyroidectomy: a single-blind prospective randomized controlled trial.
The aim of this study was to evaluate the safety and efficacy of thyroidectomy using the Harmonic ACE scalpel (HS) or the LigaSure Precise (LS) instrument in conventional thyroidectomy. ⋯ In this study, both hemostatic devices were safe and effective in terms of postoperative results and complications without any differences.
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Randomized Controlled Trial
The effects of propofol and dexmedetomidine infusion on fluid responsiveness in critically ill patients.
We studied the effects of propofol or dexmedetomidine on preload dependency and fluid responsiveness in critically ill patients. ⋯ We observed that propofol infusion, but not dexmedetomidine infusion, can increase preload dependency and fluid responsiveness in patients with circulatory failure.
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Randomized Controlled Trial
Efficacy of extracorporeal shockwave therapy for knee osteoarthritis: a randomized controlled trial.
Extracorporeal shockwave therapy (ESWT) has been widely used for pain relief and treatment of musculoskeletal disorders. We aimed to assess ESWT for knee osteoarthritis (OA) over 12 wk by comparison with placebo treatment. ⋯ ESWT is effective in reducing pain and improving knee function, with better results than placebo during the 12-wk treatment. However, further pilot studies are needed to determine whether ESWT should be recommended at an early or later stage of OA or combined with conventional therapies.
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Randomized Controlled Trial
Pulmonary acute respiratory distress syndrome: positive end-expiratory pressure titration needs stress index.
The heterogeneity of lung injury in pulmonary acute respiratory distress syndrome (ARDS) may have contributed to the greater response of hyperinflated area with positive end-expiratory pressure (PEEP). PEEP titrated by stress index can reduce the risk of alveolar hyperinflation in patients with pulmonary ARDS. The authors sought to investigate the effects of PEEP titrated by stress index on lung recruitment and protection after recruitment maneuver (RM) in pulmonary ARDS patients. ⋯ PEEP titration by stress index might be more beneficial for pulmonary ARDS patients after RM.
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Randomized Controlled Trial Comparative Study
Long-term patient perception of pain control experience after participating in a trial between patient-controlled analgesia and epidural after pectus excavatum repair with bar placement.
Pain control is the dominant management issue after bar placement for pectus excavatum. We previously conducted a prospective, randomized trial comparing patient-controlled analgesia (PCA) to thoracic epidural (EPI) documenting similar objective outcomes. Our impression is that the subjective cognitive experience differs between the groups, which impacts trial results interpretation. Therefore, we conducted a survey to ascertain patient recollection and impression of their experience. ⋯ Long-term recall after repair of pectus excavatum with bar placement does not substantially differ between those managed with an epidural or PCA.