Arch Pediat Adol Med
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Arch Pediat Adol Med · Jan 2001
Randomized Controlled Trial Clinical TrialRandomized trial of enhanced anticipatory guidance for injury prevention.
To develop and evaluate an injury prevention anticipatory guidance training program for pediatric residents. ⋯ The frequency and impact of pediatric counseling can be enhanced by experiential training that targets specific injury hazards. Because low-income families face many barriers to carrying out the recommended safety practices, supplemental strategies are needed to ensure safer homes.
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Arch Pediat Adol Med · Oct 2000
Randomized Controlled Trial Multicenter Study Clinical TrialHigher-dose intravenous magnesium therapy for children with moderate to severe acute asthma.
To evaluate the efficacy of a 40-mg/kg dose of intravenous magnesium sulfate for moderate to severe asthma exacerbations in pediatric patients. ⋯ Children treated with 40 mg/kg of intravenous magnesium sulfate for moderate to severe asthma showed remarkable improvement in short-term pulmonary function.
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Arch Pediat Adol Med · Jul 2000
Randomized Controlled Trial Clinical TrialBehavioral interventions reduce infant distress at immunization.
To assess the effectiveness of simple behavioral interventions at immunization on behavioral and biochemical indicators of distress in infants and parents in a primary care setting. ⋯ Simple behavioral interventions before immunization are associated with reductions in behavioral and biochemical indicators of infant distress.
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Arch Pediat Adol Med · May 1999
Randomized Controlled Trial Clinical TrialDorsal penile nerve block vs topical placebo for circumcision in low-birth-weight neonates.
To investigate the efficacy and safety of dorsal penile nerve block (DPNB) and eutectic mixture of lidocaine (EMLA) for palliation of pain associated with circumcision in low-birth-weight infants. ⋯ Dorsal penile nerve block is safe and effective in controlling pain associated with circumcision in low-birth-weight infants.
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Arch Pediat Adol Med · Apr 1999
Randomized Controlled Trial Multicenter Study Clinical TrialAnalgesia and sedation in preterm neonates who require ventilatory support: results from the NOPAIN trial. Neonatal Outcome and Prolonged Analgesia in Neonates.
Preterm neonates are exposed to multiple painful procedures after birth and exhibit acute physiological responses to pain. Occurrence of early intraventricular hemorrhage within 24 to 72 hours after birth suggests a role of pain and stress in the multifactorial causation of severe intraventricular hemorrhage and periventricular leukomalacia. We proposed that such neurologic outcomes in preterm neonates who require ventilatory support may be reduced by morphine analgesia or midazolam sedation compared with a placebo. ⋯ This pilot trial suggests that preemptive analgesia given by continuous low-dose morphine infusion may reduce the incidence of poor neurologic outcomes in preterm neonates who require ventilatory support. Limitations in the sample size of this pilot study suggest that these results should be confirmed in a large multicenter randomized trial.