British medical bulletin
-
Since 2015, an epidemic of Zika virus spread across the Americas. This coincided with an increased incidence of microcephaly reported at birth in Brazil, with subsequent evidence of a causal association. ⋯ Follow-up studies of affected infants are vital to inform on prognosis and guide screening programmes of the future.
-
British medical bulletin · Dec 2017
Review Comparative StudyOutcome of ankle arthrodesis and ankle prosthesis: a review of the current status.
In advanced stages of ankle osteoarthritis (OA), ankle arthrodesis (AA) or total ankle arthroplasty (TAR) may be necessary. Our purpose is to compare AA and total ankle replacement for the surgical management of end stage ankle OA. ⋯ Systematic review, level III.
-
Effective data sharing does not occur in the UK despite being essential for the delivery of high-quality genomic services to patients across clinical specialities and to optimize advances in genomic medicine. ⋯ Mechanisms to improve public trust.
-
British medical bulletin · Sep 2017
Think adult-think child! Why should staff caring for dying adults ask what the death means for children in the family?
Bereaved children and young people in the UK are 'hidden mourners'. ⋯ 'Think adult-think child' means that all staff caring for dying adults should take responsibility for asking what the death means for the children in the family, with schools, primary care and faith organizations having protocols and expertise available to support grieving children; recent catastrophes expose need for agencies to have management plans that focus on vulnerable children and young people.
-
Dystonia is a clinically heterogeneous group of hyperkinetic movement disorders. Recent advances have provided a better understanding of these conditions with significant clinical impact. ⋯ Growing understanding of the disease mechanisms involved will allow the development of targeted and disease-modifying therapies in the future.