British medical bulletin
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British medical bulletin · Mar 2024
ReviewGenetics in Parkinson's disease, state-of-the-art and future perspectives.
Parkinson's disease (PD) is the second most common neurodegenerative disorder and is clinically characterized by the presence of motor (bradykinesia, rigidity, rest tremor and postural instability) and non-motor symptoms (cognitive impairment, autonomic dysfunction, sleep disorders, depression and hyposmia). The aetiology of PD is unknown except for a small but significant contribution of monogenic forms. ⋯ The application of PRS and integrated multi-omics in PD promises to improve the personalized care of patients.
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British medical bulletin · Mar 2024
ReviewQuality of life of family carers of people living with dementia: review of systematic reviews of observational and intervention studies.
Family members are the primary source of support for the growing number of people living with dementia (PLWD) worldwide. However, caring for a person living with dementia can have detrimental impacts on the carer quality of life (QoL). This review of systematic reviews explored the factors associated with the QoL of family carers of PLWD and interventions aimed at improving their QoL. ⋯ Future research should be focused on understanding how to best implement and measure person-centred care approaches to carer QoL, including cost-effectiveness. More qualitative studies are necessary to explore carer negative and positive experiences of QoL.
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British medical bulletin · Mar 2024
Variations in older people's emergency care use by social care setting: a systematic review of international evidence.
Older adults' use of social care and their healthcare utilization are closely related. Residents of care homes access emergency care more often than the wider older population; however, less is known about emergency care use across other social care settings. ⋯ There is a paucity of published research on emergency hospital use from social care settings, particularly home care and assisted living facilities. More attention is needed on this area, with standardized definitions to enable comparisons between studies.
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British medical bulletin · Dec 2023
ReviewEnhancing patient-centred care in dentistry: a narrative review.
Patient-centred care (PCC) is widely used within the medical setting, but there is a need for more research on PCC implementation in dentistry. ⋯ A theory-derived model of PCC explicitly designed for the dental setting was identified. This serves as a starting point to enhance PCC in dentistry, though further research is needed to empirically test the implementation of this model.
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British medical bulletin · Dec 2023
ReviewInterventions to tackle health inequalities in cardiovascular risks for socioeconomically disadvantaged populations: a rapid review.
Cardiovascular disease (CVD) has shown significant health inequalities for people with low socioeconomic status associated with more risk factors. This review was to synthesize interventions that targeted CVD risks and outcomes among socioeconomically disadvantaged populations and to understand the impact associated with these interventions. ⋯ Research is needed with mixed evidence using real world evaluation and lived experience combined with health economic evaluation, on both mental and physical health outcomes.