Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde
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Randomized Controlled Trial Comparative Study
Effect of volume used in sub-Tenon's anesthesia on efficacy and intraocular pressure in vitreoretinal surgery.
To compare the effect of volumes used in sub- Tenon's anesthesia on efficacy and intraocular pressure (IOP) in vitreoretinal surgery. ⋯ Sub-Tenon's anesthesia is effective in vitreoretinal surgery. It would appear that a 3-5-ml volume of anesthetic is safe, when considering the associated complications.
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To study the antimicrobial activity of silicone oil against Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa and Candida albicans in vitro. ⋯ Silicone oil has a significant antimicrobial activity against S. aureus, S. epidermidis, P. aeruginosa and C. albicans in vitro.
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Cocaine was brought to Europe after the discovery of America. In the 19th century, the active component of coca leaves, named cocaine, was extracted and several researchers started experimenting with the substance, describing many physiological and pathological effects of its action. The first scholar to practically demonstrate the possibility of using cocaine solution in medicine, mostly ophthalmology, was Carl Koller. ⋯ Halsted and Hall reported the first successful nerve block of the interior dental nerve with 4% cocaine solution. In 1892, Schleich published the results of his studies in which he used a 0.1-0.2% solution of cocaine hydrochloride intra- and subcutaneously, introducing the so-called infiltration anaesthesia. At the end of the 19th century it was, however, demonstrated that cocaine possessed many undesirable effects, including addiction, which triggered off interest in other, less toxic, anaesthetics.