Turk J Gastroenterol
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Turk J Gastroenterol · Jun 2012
Case ReportsFascioliasis: 3 cases with three different clinical presentations.
Fascioliasis, which is a zoonotic infestation caused by the trematode Fasciola hepatica (liver fluke), is primarily a disease of herbivorous animals such as sheep and cattle. Humans become accidental hosts through ingesting uncooked aquatic plants such as watercress. ⋯ As a result of newly introduced serological assays facilitating the diagnosis, there has been an increase in the number of reported cases. Here, we report the clinical and laboratory assessment and therapeutic approach of a series of three cases diagnosed (in order of) one week, three months and one and a half years after presentation of the first symptoms of the disease.
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Turk J Gastroenterol · Jun 2012
Calretinin immunohistochemistry in Hirschsprung's disease: An adjunct to formalin-based diagnosis.
This study was designed to assess the utility of calretinin immunohistochemistry in the diagnosis of Hirschsprung's disease. ⋯ Calretinin immunohistochemistry was found to be highly sensitive and specific in detecting aganglionic segments. New research should be conducted in order to clarify calretinin staining patterns of the transitional zone, rare Hirschsprung's disease types, pure hypoganglionosis patients, and the anorectal junction, and for the mapping of fetal and neonatal colonic specimens. The technique seemed very effective for lowering the need for excessive sectioning and practical regarding the erratic nature of the acetylcholinesterase staining.