Bratisl Med J
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Randomized Controlled Trial
Prevention of postoperative nausea and vomiting with a small dose of propofol combined with dexamethasone 4 mg or dexamethasone 8 mg in patients undergoing middle ear surgery: a prospective, randomized, double-blind study.
Postoperative nausea and vomiting (PONV) is a common complication after middle ear surgery. We have aimed to compare the administration of a subhypnotic dose of propofol with dexamethasone 4 mg or 8 mg and placebo in prevention of postoperative nausea and vomiting (PONV) after middle ear surgery. ⋯ The administration of a subhypnotic dose of propofol plus 4 mg of dexamethasone at the end of surgery was found to be at least as effective as propofol plus 8 mg of dexamethasone in preventing the PONV in the early postoperative period in adult patients undergoing middle ear surgery (Tab. 4, Ref. 34).
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Randomized Controlled Trial Comparative Study
The comparison of the effects of T-piece and CPAP on hemodynamic parameters, arterial blood gases and success of weaning.
Weaning from mechanically ventilation is a period of transition from total ventilatory support to spontaneous breathing. The aim of this study was to compare the effects of T-Piece and continuous positive airway pressure (CPAP) on hemodynamic parameters, arterial blood gases and success of weaning. In a prospective, randomized, controlled trial, 40 consecutive patients requiring mechanically ventilation in our 8-bed adult general intensive care unit (ICU) for >48 hrs were considered eligible for this study. ⋯ There were no significant differences within and between T-piece and CPAP groups according to hemodynamic parameters and arterial blood gases at the weaning period. The number of patients who could be unsuccessful weaned in the T-piece group was higher than the number of patients in the group CPAP (p < 0.001, p < 0.01). Whether, the technique used to wean patients, in this setting, resulted in a clinically relevant improvement in the outcomes addressed above requires further carefully designed, randomized, controlled trials (Tab. 4, Ref. 25).
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Randomized Controlled Trial Comparative Study
The comparison of ultrasound treatment and local steroid injection plus splinting in the carpal tunnel syndrome: a randomized controlled trial.
This study aimed to compare the efficacy of ultrasound treatment to local corticosteroid injection plus splinting in carpal tunnel syndrome (CTS). There is still limited knowledge on the efficacy of conservative treatment options for CTS. ⋯ Both ultrasound treatment and corticosteroid injection plus splinting were effective on the clinical symptoms and the electrophysiological findings of CTS. Thus, the ultrasound therapy may be an alternative treatment for CTS, particularly in patient who do not accept injection or splinting (Tab. 3, Fig. 2, Ref. 36).
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Randomized Controlled Trial Comparative Study
Direct current therapy with/without lidocaine iontophoresis in myofascial pain syndrome.
This study aimed to assess the effectiveness of lidocaine iontophoresis for inactivation of trigger points (TrPs) in the treatment of myofascial pain syndrome (MPS). ⋯ Direct current therapy with/without lidocaine iontophoresis were determined to be effective treatment modalities in TrP management. These treatment modalities are non-invasive, cost effective and provide long term improvement. Thus, these modalities could be safely used in the management of MPS with minimal side effects, particularly if patients may not accept injection or other treatments (Tab. 3, Ref. 44). Full Text (Free, PDF) www.bmj.sk.
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Randomized Controlled Trial Comparative Study
The epidural postoperative analgesia after a major urological procedures--a comparison of trimecaine and morphine to bupivacaine and fentanyl.
To compare the analgesic potency and side effects of epidural combination trimecaine with morphine and bupivacaine with fentanyl in postoperative analgesia after a major urological surgery. ⋯ The combination of epidural trimecaine with morphine after a major urological surgery provides a superior analgesia with fewer side effects when compared to epidurally delivered bupivacaine with fentanyl (Tab. 2, Fig. 5, Ref. 17). Full Text (Free, PDF) www.bmj.sk.