Gac Med Mex
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Multicenter Study
Towards objectivity in ethical assessment: legibility as part of informed consent form comprehension.
The experience on informed consent form (ICF) readability at the Research Ethics Committee of the National Institute of Cancerology of Mexico (INCan) is described. ⋯ It is necessary to have tools that provide objectivity to the evaluation of ICFs under investigation by ethics committees, which should be indicators of their comprehension, such as readability of the documents.
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Randomized Controlled Trial Multicenter Study
Efficacy and safety comparative study of dexrabeprazole vs. esomeprazole for the treatment of gastroesophageal reflux disease.
A national survey in the general population showed that gastroesophageal reflux disease (GERD) is highly prevalent in Mexico. ⋯ In the treatment of non-erosive GERD, the use of dexrabeprazole at 10 mg/day is as effective as esomeprazole 20 mg/day, with the advantage that the dose is lower with an appropriate safety profile.
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Multicenter Study
Approach to cardiology residents clinical aptitude evaluation. Multicenter design.
To the best of our knowledge, the research herein presented is the first multicenter study in Mexico to analyze the development of clinical aptitude in medical units that train cardiologists. ⋯ The degree of clinical aptitude development can be considered intermediate in all three academic sites, probably because the instrument explored problematized clinical situations that required for the residents to critically reflect on their clinical experience.
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Multicenter Study
Triglyceride-glucose index impact on in-hospital mortality in acute myocardial infarction. Results from the RECUIMA multicenter registry.
The triglyceride-glucose (TyG) index is considered a new marker of insulin resistance, and is associated with the development of cardiovascular diseases. ⋯ The TyG index constitutes an independent risk factor of in-hospital mortality in patients with acute ST-elevation myocardial infarction.
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Multicenter Study
Clinical features of patients with Rocky Mountain spotted fever, dengue and chikungunya infection.
Clinical distinction between arbovirus infections and those caused by rickettsia is crucial to initiate appropriate medical treatment. ⋯ Rash on the palms and soles, edema and absence of pruritus, together with high levels of direct bilirubin and severe thrombocytopenia could be useful indicators to differentiate patients at RMSF advanced stages from those with dengue and chikungunya.