Niger J Clin Pract
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Vesicovaginal and rectovaginal fistulas may develop after pelvic metastasis of ovarian carcinoma. Purulent discharge from the vagina results in frequent vaginal or urinary tract infections, and triggers chronic inflammation. These incapacitating symptoms create serious medical and psychosocial problems, and result in low self-esteem and QoL. ⋯ Surgery was performed successfully. However, we had to deal with complications, such as electrolyte imbalance, wound infection and continuing SIRS. Cumulative inflammatory burden caused by advanced carcinoma itself and its complications creates serious medical and psychosocial problems and should be managed with patience.
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Randomized Controlled Trial
Anti-microbial efficacy of root canal preparation in deciduous teeth with manual and rotary files: A randomized clinical trial.
In a pulpectomy, the eradication of microbes from the primary root canal is accomplished through biomechanical preparation, which could be carried out with either manual or rotary instruments. ⋯ Manual and rotary files were equally effective in removing root canal microbes. Biomechanical preparation with a KedoS Square rotary file resulted in greater microbial efficacy. Hence In children, effective root canal cleaning in a short period of time is a major consideration.
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The C-reactive protein (CRP)/albumin ratio (CAR) is one of the new tools to assess the severity of inflammation. It is used to determine clinical severity and prognosis in many diseases. ⋯ CAR is a valuable biomarker for predicting prognosis, as well as follow-ups of pregnant COVID-19 patients.
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Children suffering from epilepsy are maintained on antiepileptic drugs (AED) to ensure a reasonable quality of life. These drugs, however, are not without side effects. Notable among which is interference with the metabolism of folate with its attendant clinical implications such as megaloblastic anemia and bleeding diathesis. ⋯ The mean serum folate level in subjects was significantly lower than the value in controls; but was comparable in subjects on carbamazepine, phenobarbitone, and valproate as monotherapy. There was no correlation between the duration of AED use and mean serum folate levels.
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Allergic rhinitis (AR) is a multifocal IgE-mediated type I hypersensitivity reaction involving nasal mucosa characterized by excessive sneezing, watery rhinorrhea, nasal itching, nasal stuffiness, and eyes itching. Tympanometry is a simple, rapid, and objective test that can be easily carried out. The use of tympanometry in clinical setting can improve detection of middle ear effusion and other middle ear abnormalities. AR has been found to be one of the predisposing factors to developing Otitis Media with Effusion (OME) in children. ⋯ Participants with AR were found to have more abnormalities of tympanometric parameters and higher prevalence of type B tympanogram suggesting OME than controls.