Niger J Clin Pract
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Adiponectin (ApN) is a 244-amino acid protein mainly secreted from the adipose tissue and involved in various physiological functions. ApN exerts its metabolic effects by binding to two major receptors: adiponectin receptor-1 (Adipo-R1) and adiponectin receptor-2 (Adipo-R2). Recent studies have reported ApN's involvement in the progression of cancer. However, there are no studies evaluating the relationship between Adipo-R1/R2 expression and gastric intestinal metaplasia (IM), which is a predisposing factor in gastric cancer (GC) development, and Helicobacter pylori H. pylori infection. ⋯ The resulting data suggests that ApN plays a role in GC processes via Adipo-R1/-R2 receptors.
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To establish normative values for functional, lateral, and Oblique Direction Reach Tests (ODRT) and to assess the validity and reliability of the ODRT in Saudi children of age 6-15 years. ⋯ : We established the normal values for functional, lateral, and ODRT in 6-15 years of Saudi children. We found that ODRT is a valid and reliable for measuring limits of stability in oblique direction.
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Observational Study
Clinicopathological comparison of VHL expression as a prognostic tumor marker in renal cell carcinoma: A single center experience.
To assess the VHL gene expression as a prognostic marker in Renal Cell Carcinoma (RCC) and compare it with clinicopathologic features. ⋯ Complete loss of VHL expression was noted in majority of the specimens that leads to the development of RCC. Smoking has been found to be statistically significant in tumors that retain VHL expression which may contributes to more aggressive form of tumor. Association between rT staging, nature of lesion and cut surface, HPE type, pT staging, HPE grade, necrosis and lympho-vascular invasion were also found to be statistically significant.
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To determine the prevalence of refractive errors and causes of visual impairment in school children in Enugu State, South-eastern Nigeria. ⋯ The prevalence of refractive error in this study is low, with myopia being more common. Despite the low prevalence of refractive error, school vision screening is still important for African children as it serves as an opportunity to identify other ocular morbidities among the children.
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The purpose of this study is to understand healthcare students' knowledge of COVID-19 and the precautionary behaviors they practiced in Saudi Arabia during the MERS-CoV2 outbreak. ⋯ While most health students were knowledgeable about most aspects of COVID-19, others did not follow universal precautions during the outbreak, which identifies better incorporation of such information in students' academic programs.