Niger J Clin Pract
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Deep-lobe tumors have been shown to possess a significantly thicker capsule with less tumor penetration compared to superficial tumors. Thus, more conservative surgical approaches, rather than aggressive methods, have been proposed for treating benign deep-lobe tumors of the parotid gland. ⋯ SDLP may facilitate the safe surgical removal of benign lesions located in the deep lobe of the parotid gland, with oncological safety, reduced complication rates, and improved cosmetic outcomes.
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This study investigates the association between the presence of diverticula in the colon and esophagus and the occurrence of hiatal hernia, seeking to understand potential shared pathophysiological underpinnings and risk factors. ⋯ The study demonstrates a notable association between hiatal hernias and the presence of both colonic and esophageal diverticula, suggesting common pathophysiological processes. These findings highlight the need for further research into shared risk factors and mechanisms underlying these conditions, potentially guiding improved management strategies for affected patients.
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Colorectal carcinoma (CRC) is the most common gastrointestinal malignancy in Nigeria with a dismal 5-year survival rate. Interactions between the CD8+ T-lymphocytes and the immune checkpoints such as cytotoxic T-lymphocyte antigen-4 (CTLA-4) and programmed death-ligand 1 (PD-L1) expressions are important. Novel antibodies have been developed against these immune checkpoints and have been found to improve clinical outcome in many solid organ malignancies. ⋯ PD-L1 expression in CRC was low (5.6%) and showed strong associations with higher tumor grades (P < 0.013), right-sided tumors (P < 0.002), and rectal cancer. There was no association with age, tumor stage, and lymph node status.
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Brucellosis is the most common zoonosis worldwide. Prevention of brucellosis is based on surveillance and prevention of risk factors. ⋯ Findings from validity and reliability studies show that the Turkish version of the BPQ is a valid and reliable scale in Turkish society and culture.
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Dermatofibrosarcoma protuberan is a locally aggressive tumor that can be challenging to manage if it becomes recurrent. The best attempt at achieving cure is the first surgery. ⋯ Multidisciplinary care offers good outcomes when reconstructive needs are catered for. In our resource-poor setting, it will be beneficial to have an adequate (more than 5 cm margin) excision margin followed by reconstruction of defects by surgeons with adequate training in management of the pathology and tissue reconstruction.