Saudi Med J
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To evaluate whether hypothyroidism is a risk factor for transient ischemic attack (TIA). ⋯ Hypothyroidism, particularly clinical hypothyroidism, may be an independent risk factor for TIA.PROSPERO No. ID: CRD42024552608.
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Meta Analysis
Effect of laparoscopic intracorporeal reinforcing sutures to prevent anastomotic leakage: A meta-analysis.
To assess the effectiveness of reinforcing sutures after surgery for rectal cancer and its associated impact on postoperative recovery. Anastomotic leakage (AL) is a common and serious complication after anteriorrectal resection. It is currently unclear whether laparoscopic intracorporeal reinforcingsutures can effectively reduce the incidence of AL. ⋯ The occurrence of AL can be greatly decreased through the use of a laparoscopic approach for anastomotic reinforcement, which may be a better option after radical surgery for rectal patients. However, more RCT studies with large sample sizes are needed.PROSPERO: CRD42024548847.
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To systematically review evidence on the prevalence of the JAK2V617F (JAK2) mutation and polycythemia vera (PV) among all blood donors, focusing on those with elevated hematocrit. Although blood donors are generally healthy, considering a preclinical stage of myeloproliferative neoplasm, especially in those with polycythemia, is crucial. Evidence on managing these donors is limited. ⋯ The prevalence of the JAK2 mutation among blood donors is similar to the general population's but slightly higher among repeat donors with elevated hematocrit. Further research is necessary to establish definitive upper hemoglobin limits for donor deferral.PROSPERO No.: CRD42023456878.
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Review Meta Analysis
Geriatric nutritional risk index predicts postoperative delirium in elderly: A meta-analysis.
To review current evidence on using the geriatric nutritional risk index (GNRI) in predicting postoperative delirium (POD) in elderly patients. ⋯ Therefore, moderate and high GNRI increased the risk of POD in elderly patients.
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To evaluate the effectiveness and safety of rivaroxaban anticoagulation in COVID-19 patients. ⋯ Rivaroxaban may reduce thrombotic events in COVID-19 patients, but it does not appear to have an advantage over heparin or LMWH, and it may increase the risk of bleeding.INPLASY Reg. No.: INPLASY 202370097.